GLRX3

Across TCGA patient cohorts, GLRX3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,535 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GLRX3-associated genes across cancer lineages are AMY2B, BUB3, and ABRAXAS2. Each is linked with GLRX3 in more than 7 cancer types. Because this analysis shows association rather than direction, both GLRX3-to-partner and partner-to-GLRX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLRX3 versus AMY2B in PDAC, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRX3→partner) and Y-score (partner→GLRX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	AMY2B →	-1.984	-0.410	<.001	<.001	3	8
UCEC	BUB3 →	+0.464	+0.227	.005	.008	3	7
OV	ABRAXAS2 →	+0.412	+0.239	<.001	<.001	3	7
LSCC	AP3M1 →	+0.392	+0.356	<.001	<.001	3	7
LSCC	TIMM23 →	+0.615	+0.482	<.001	<.001	3	7
BRCA	CEP55 →	+1.098	+0.301	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,535 associations by consensus.

GLRX3 vs AMY2B — PDAC

Explore this scatter interactively →