GLRX3

Across TCGA patient cohorts, GLRX3 mutation is significantly associated with the RNA expression of many other genes, with 764 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLRX3-associated genes across cancer lineages are CCDC75P1, RNU6-879P, and MIR3679. Each is linked with GLRX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLRX3-to-partner and partner-to-GLRX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC75P1 grouped by GLRX3-low versus GLRX3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRX3→partner) and Y-score (partner→GLRX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CCDC75P1 →	+0.057	+4.973	<.001	.009	3	2
UCEC	RNU6-879P →	+0.340	+2.292	.005	<.001	3	2
BLCA	MIR3679 →	+0.482	+5.106	.002	.008	3	2
SKCM	OR5M1 →	+0.563	+5.328	<.001	.003	3	1
SKCM	PRSS58 →	+0.116	+4.875	<.001	.002	3	1
SKCM	LINC02304 →	+0.084	+5.624	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 764 associations by consensus.

CCDC75P1 by GLRX3 expression — BLCA

Explore this box plot interactively →