GLRX3

Across TCGA cell cohorts, GLRX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,431 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GLRX3-associated GO terms across cancer lineages are Spindle elongation, DNA replication initiation, and Metaphase chromosome alignment. Each is linked with GLRX3 in more than 14 cancer types. Because this analysis shows association rather than direction, both GLRX3-to-partner and partner-to-GLRX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by GLRX3-low versus GLRX3-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRX3→partner) and Y-score (partner→GLRX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Spindle elongation →	+0.255	+1.075	.001	.008	3	15
PANCREAS	DNA replication initiation →	+0.140	+0.718	.001	.002	2	13
UPPER_AERODIGESTIVE_TRACT	Metaphase chromosome alignment →	+0.098	+0.790	.003	<.001	3	12
LUNG_NSCLC_LUAD	Kinetochore organization →	+0.081	+0.606	.004	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Chromosome localization →	+0.111	+0.981	.003	<.001	3	12
BLOOD_Myeloma	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.169	+1.258	.004	.001	1	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,431 associations by consensus.

Spindle elongation by GLRX3 expression — BLOOD_Myeloma

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