GLRX2

Across TCGA patient cohorts, GLRX2 mutation is significantly associated with the RNA expression of many other genes, with 320 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLRX2-associated genes across cancer lineages are WBP1LP8, MIR6853, and MIR7159. Each is linked with GLRX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLRX2-to-partner and partner-to-GLRX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WBP1LP8 grouped by GLRX2-low versus GLRX2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRX2→partner) and Y-score (partner→GLRX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WBP1LP8 →	+0.106	+8.057	<.001	.005	3	1
BRCA	MIR6853 →	+0.242	+8.057	<.001	.005	3	1
BRCA	MIR7159 →	+0.820	+5.317	<.001	.006	3	1
BRCA	RNU6-706P →	+0.395	+7.471	<.001	.008	3	1
BRCA	MIR548AD →	+0.225	+7.471	<.001	.008	3	1
BRCA	RNU6-974P →	+0.228	+7.471	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 320 associations by consensus.

WBP1LP8 by GLRX2 expression — BRCA

Explore this box plot interactively →