GLRX2

Across TCGA cell cohorts, GLRX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,356 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GLRX2-associated GO terms across cancer lineages are DNA protection, Response to redox state, and Negative regulation of autophagy. Each is linked with GLRX2 in more than 14 cancer types. Because this analysis shows association rather than direction, both GLRX2-to-partner and partner-to-GLRX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA protection grouped by GLRX2-low versus GLRX2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRX2→partner) and Y-score (partner→GLRX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	DNA protection →	+0.234	+1.465	<.001	<.001	3	15
BONE	Response to redox state →	+0.143	+0.897	<.001	.002	3	10
OESOPHAGUS	Negative regulation of autophagy →	-0.105	-1.093	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	tRNA 5'-leader removal →	+0.129	+0.976	.004	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening →	-0.067	-0.530	.006	.006	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic spindle assembly checkpoint signaling →	+0.185	+0.792	<.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,356 associations by consensus.

DNA protection by GLRX2 expression — LIVER

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