GLRX

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GLRX RNA expression is significantly associated with the protein abundance of many other proteins, with 22,779 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GLRX-associated proteins across cancer lineages are MLKL, SEC24A, and ADNP. Each is linked with GLRX in more than 7 cancer types. Because this analysis shows association rather than direction, both GLRX-to-partner and partner-to-GLRX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLRX versus MLKL in GBM, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRX→partner) and Y-score (partner→GLRX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMLKL →+0.563+0.525<.001<.00138
LSCCSEC24A →+0.414+0.667<.001<.00137
GBMADNP →-0.380-0.559<.001<.00137
OVFMNL1_S184 →+1.266+1.368<.001<.00137
GBMGMIP →+0.401+0.457<.001<.00137
GBMAMPD3 →+0.747+0.639<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,779 associations by consensus.

GLRX vs MLKL — GBM

Per-sample scatter of GLRX vs MLKL in GBM (Pearson r = 0.60).

Explore this scatter interactively →

Exploration