GLRX

Across TCGA patient cohorts, GLRX protein abundance is significantly associated with the RNA expression of many other genes, with 18,820 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GLRX-associated genes across cancer lineages are CYTH4, PIK3CG, and LAX1. Each is linked with GLRX in more than 7 cancer types. Because this analysis shows association rather than direction, both GLRX-to-partner and partner-to-GLRX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLRX versus CYTH4 in GBM, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRX→partner) and Y-score (partner→GLRX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.095	+0.500	<.001	<.001	3	8
LSCC	PIK3CG →	+1.068	+0.656	<.001	<.001	3	8
LSCC	LAX1 →	+1.359	+0.641	<.001	<.001	3	8
OV	DOCK2 →	+1.089	+0.635	<.001	<.001	3	8
UCEC	IRF4 →	+1.258	+0.628	<.001	<.001	3	8
LSCC	FCRL5 →	+1.413	+0.622	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,820 associations by consensus.

GLRX vs CYTH4 — GBM

Explore this scatter interactively →