GLRX

Across TCGA cell cohorts, GLRX RNA expression is significantly associated with the go_rna of many other GO terms, with 4,169 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GLRX-associated GO terms across cancer lineages are Nucleobase-containing small molecule interconversion, Positive regulation of membrane potential, and Negative regulation of Rho protein signal transduction. Each is linked with GLRX in more than 15 cancer types. Because this analysis shows association rather than direction, both GLRX-to-partner and partner-to-GLRX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleobase-containing small molecule interconversion grouped by GLRX-low versus GLRX-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRX→partner) and Y-score (partner→GLRX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Nucleobase-containing small molecule interconversion →	+0.306	+4.097	<.001	<.001	3	16
SOFT_TISSUE	Positive regulation of membrane potential →	+0.161	+2.818	<.001	.001	2	15
SOFT_TISSUE	Negative regulation of Rho protein signal transduction →	+0.132	+2.490	<.001	<.001	3	10
SOFT_TISSUE	Substrate adhesion-dependent cell spreading →	+0.191	+3.722	<.001	<.001	3	10
SOFT_TISSUE	Viral process →	+0.089	+3.976	<.001	<.001	3	9
SOFT_TISSUE	Positive regulation of cell junction assembly →	+0.084	+3.121	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,169 associations by consensus.

Nucleobase-containing small molecule interconversion by GLRX expression — LUNG_NSCLC_LUSC

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