GLRA3

Across TCGA patient cohorts, GLRA3 mutation is significantly associated with the RNA expression of many other genes, with 1,669 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLRA3-associated genes across cancer lineages are FAM177A1, NTAN1, and NCAPH2. Each is linked with GLRA3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLRA3-to-partner and partner-to-GLRA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM177A1 grouped by GLRA3-low versus GLRA3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRA3→partner) and Y-score (partner→GLRA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM177A1 →	+0.273	+1.726	.009	.002	3	3
UCEC	NTAN1 →	+0.457	+2.534	<.001	<.001	3	3
UCEC	NCAPH2 →	+0.528	+2.000	<.001	.001	3	3
UCEC	ACYP1 →	+0.444	+3.064	<.001	<.001	3	3
SKCM	RPL23AP82 →	+0.497	+2.725	<.001	<.001	3	3
UCEC	NDUFA6 →	+0.399	+2.632	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,669 associations by consensus.

FAM177A1 by GLRA3 expression — UCEC

Explore this box plot interactively →