GLRA3

Across TCGA cell cohorts, GLRA3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GLRA3-associated genes across cancer lineages are FTMT, MMP27, and KRTAP12-3. Each is linked with GLRA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLRA3-to-partner and partner-to-GLRA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTMT grouped by GLRA3-low versus GLRA3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRA3→partner) and Y-score (partner→GLRA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	FTMT →	+0.086	+5.977	<.001	.001	3	1
BLOOD_Leukemia	MMP27 →	+0.019	+4.969	<.001	.003	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.061	+4.539	<.001	.007	3	1
SKIN	NCR2 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	CLEC9A →	+0.012	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

FTMT by GLRA3 expression — SOFT_TISSUE

Explore this box plot interactively →