GLRA1

Across TCGA cell cohorts, GLRA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,538 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GLRA1-associated GO terms across cancer lineages are mRNA splice site recognition, Regulation of mRNA splicing, via spliceosome, and Nuclear export. Each is linked with GLRA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GLRA1-to-partner and partner-to-GLRA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by GLRA1-low versus GLRA1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLRA1→partner) and Y-score (partner→GLRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.107	+0.028	<.001	.007	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.080	+0.050	<.001	.006	3	6
BLOOD_Lymphoma	Nuclear export →	+0.080	+0.028	<.001	<.001	3	6
SKIN	Detection of visible light →	-0.275	-0.069	<.001	<.001	3	6
PANCREAS	Mitochondrial mRNA polyadenylation →	+0.096	+0.024	.005	.005	3	6
BLOOD_Lymphoma	Viral transcription →	+0.076	+0.021	.003	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,538 associations by consensus.

mRNA splice site recognition by GLRA1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →