Across TCGA pan-cancer cohorts, GLMP mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of GLMP’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where GLMP mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types GLMP is over-expressed in tumor, although a few such as LSCC show the opposite, repressed pattern.

HNSC, LSCC, and LUAD are the cancer types where GLMP tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GLMP mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.297	.001	5	view →
LSCC	All	All	−0.141	<.001	4	view →
LUAD	Female	II,III,IV	+0.269	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: GLMP RNA expression & survival · all GLMP data types