GLMN

Across TCGA pan-cancer cohorts, GLMN mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GLMN data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GLMN mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated GLMN expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC, LUAD, and LSCC are the cancer types where GLMN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	1.000	0.312	.003	32	view →
LUAD	DFS	Median	II,III,IV	0.955	0.759	.004	26	view →
LSCC	DFS	Tertile	All	1.000	0.352	<.001	8	view →
GBM	OS	Tertile	All	1.000	0.812	<.001	3	view →
PDAC	DFS	Median	III,IV	0.471	0.252	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GLMN–UCEC (OS)

Open the UCEC breakdown →