GLMN

Across TCGA patient cohorts, GLMN mutation is significantly associated with the RNA expression of many other genes, with 819 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLMN-associated genes across cancer lineages are MTND2P33, TRAJ43, and LINC02089. Each is linked with GLMN in more than 1 cancer types. Because this analysis shows association rather than direction, both GLMN-to-partner and partner-to-GLMN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND2P33 grouped by GLMN-low versus GLMN-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLMN→partner) and Y-score (partner→GLMN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MTND2P33 →	+0.080	+5.219	<.001	.006	3	2
BLCA	TRAJ43 →	+1.154	+5.588	<.001	.004	3	2
LUSC	LINC02089 →	+0.119	+5.093	.004	.008	3	2
SKCM	LINC02401 →	+0.011	+4.680	<.001	.007	3	2
HNSC	RNU6-956P →	+0.763	+7.954	<.001	.008	3	2
LUAD	SLC25A5P9 →	+0.042	+5.217	.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 819 associations by consensus.

MTND2P33 by GLMN expression — READ

Explore this box plot interactively →