GLIPR2

Across TCGA patient cohorts, GLIPR2 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLIPR2-associated genes across cancer lineages are A-Raf_pS299, PRDX1, and JNK2. Each is linked with GLIPR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLIPR2-to-partner and partner-to-GLIPR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by GLIPR2-low versus GLIPR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLIPR2→partner) and Y-score (partner→GLIPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.184	-3.000	.003	.036	3	1
UCEC	PRDX1 →	-0.270	-3.321	.012	.010	3	1
UCEC	JNK2 →	+0.378	+3.009	<.001	.019	2	1
UCEC	P-Cadherin →	-0.189	-3.308	.012	.010	2	1
UCEC	Annexin-1 →	+0.898	+3.321	.001	.010	1	2
UCEC	c-Myc →	-0.290	-3.308	.024	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

A-Raf_pS299 by GLIPR2 expression — UCEC

Explore this box plot interactively →