GLIPR1L2

Across TCGA patient cohorts, GLIPR1L2 mutation is significantly associated with the RNA expression of many other genes, with 1,813 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLIPR1L2-associated genes across cancer lineages are NOP10, SERPINA11, and TAF13. Each is linked with GLIPR1L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLIPR1L2-to-partner and partner-to-GLIPR1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOP10 grouped by GLIPR1L2-low versus GLIPR1L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLIPR1L2→partner) and Y-score (partner→GLIPR1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NOP10 →	+0.524	+2.662	<.001	<.001	3	2
UCEC	SERPINA11 →	-1.048	-3.759	.007	<.001	3	2
UCEC	TAF13 →	+0.556	+2.230	.003	.006	3	2
UCEC	LINC01072 →	+0.113	+2.073	<.001	.005	3	2
UCEC	BAALC-AS1 →	-0.517	-2.630	<.001	<.001	3	2
UCEC	GPN3 →	+0.545	+2.223	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,813 associations by consensus.

NOP10 by GLIPR1L2 expression — UCEC

Explore this box plot interactively →