GLIPR1L2

Across TCGA cell cohorts, GLIPR1L2 mutation is significantly associated with the drug of many other genes, with 55 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GLIPR1L2-associated genes across cancer lineages are Niraparib, AZ960, and Luminespib. Each is linked with GLIPR1L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLIPR1L2-to-partner and partner-to-GLIPR1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Niraparib grouped by GLIPR1L2-low versus GLIPR1L2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLIPR1L2→partner) and Y-score (partner→GLIPR1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Niraparib →	+0.519	+2.678	.002	.037	3	1
LARGE_INTESTINE	AZ960 →	+0.769	+2.646	.007	.047	3	1
LARGE_INTESTINE	Luminespib →	+0.657	+2.646	.031	.047	3	1
LARGE_INTESTINE	GSK2801 →	+0.377	+2.649	.017	.046	3	1
LARGE_INTESTINE	RVX-208 →	+0.361	+2.646	.019	.047	3	1
LARGE_INTESTINE	AZD5153 →	+0.569	+2.649	.023	.046	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Niraparib by GLIPR1L2 expression — LARGE_INTESTINE

Explore this box plot interactively →