GLIPR1L1

Across TCGA patient cohorts, GLIPR1L1 mutation is significantly associated with the RNA expression of many other genes, with 1,120 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLIPR1L1-associated genes across cancer lineages are RNA5SP369, RPL31P47, and RNA5SP303. Each is linked with GLIPR1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLIPR1L1-to-partner and partner-to-GLIPR1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP369 grouped by GLIPR1L1-low versus GLIPR1L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLIPR1L1→partner) and Y-score (partner→GLIPR1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP369 →	+0.424	+2.416	<.001	.001	3	2
UCEC	RPL31P47 →	+0.319	+2.269	<.001	.003	3	2
UCEC	RNA5SP303 →	+0.193	+2.452	<.001	.008	3	2
UCEC	RNU6-358P →	+0.282	+2.648	.002	.002	3	2
SKCM	OR13C3 →	+0.054	+6.080	<.001	.002	3	2
UCEC	YTHDF3-AS1 →	+0.626	+3.724	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,120 associations by consensus.

RNA5SP369 by GLIPR1L1 expression — UCEC

Explore this box plot interactively →