GLIPR1L1

Across TCGA cell cohorts, GLIPR1L1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GLIPR1L1-associated genes across cancer lineages are CCL18, OR1L3, and DPRX. Each is linked with GLIPR1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLIPR1L1-to-partner and partner-to-GLIPR1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL18 grouped by GLIPR1L1-low versus GLIPR1L1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLIPR1L1→partner) and Y-score (partner→GLIPR1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCL18 →	+0.097	+4.415	<.001	.007	3	2
LUNG_NSCLC_LUAD	OR1L3 →	+0.032	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	DPRX →	+0.283	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CCL18 by GLIPR1L1 expression — LARGE_INTESTINE

Explore this box plot interactively →