GLIPR1

Across TCGA patient cohorts, GLIPR1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,365 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GLIPR1-associated genes across cancer lineages are SAMHD1, TLR8, and IL21R. Each is linked with GLIPR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GLIPR1-to-partner and partner-to-GLIPR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLIPR1 versus SAMHD1 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLIPR1→partner) and Y-score (partner→GLIPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAMHD1 →	+0.652	+0.948	<.001	<.001	3	5
OV	TLR8 →	+1.029	+0.699	.001	<.001	3	5
GBM	IL21R →	+1.256	+0.989	<.001	<.001	3	5
OV	JAK3 →	+0.882	+0.659	<.001	<.001	3	5
GBM	PIK3CG →	+0.999	+1.125	<.001	<.001	3	5
OV	TFEC →	+0.769	+0.529	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,365 associations by consensus.

GLIPR1 vs SAMHD1 — GBM

Explore this scatter interactively →