GLIPR1

Across TCGA cell cohorts, GLIPR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,993 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GLIPR1-associated GO terms across cancer lineages are Negative regulation of plasminogen activation, Negative regulation of Rho protein signal transduction, and Cellular response to environmental stimulus. Each is linked with GLIPR1 in more than 15 cancer types. Because this analysis shows association rather than direction, both GLIPR1-to-partner and partner-to-GLIPR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of plasminogen activation grouped by GLIPR1-low versus GLIPR1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLIPR1→partner) and Y-score (partner→GLIPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of plasminogen activation →	+1.162	+3.591	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Negative regulation of Rho protein signal transduction →	+0.175	+2.988	.001	.001	3	15
LUNG_NSCLC_LUSC	Cellular response to environmental stimulus →	+0.065	+2.672	.002	.008	3	14
BONE	Regulation of protein maturation →	+0.221	+3.666	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of smooth muscle cell-matrix adhesion →	+1.283	+3.187	.001	<.001	3	14
BONE	Positive regulation of stress fiber assembly →	+0.218	+3.891	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,993 associations by consensus.

Negative regulation of plasminogen activation by GLIPR1 expression — BONE

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