GLIDR

Across TCGA pan-cancer cohorts, GLIDR RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated GLIDR data layer compared with 2 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher GLIDR RNA is associated with better overall survival. In most high-consensus cancer types, elevated GLIDR expression acts as an unfavorable survival marker, although some lineages such as MESO and KIRC show a favorable association.

MESO, KIRC, and BRCA are the cancer types where GLIDR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.671	0.418	<.001	86	view →
KIRC	OS	Tertile	All	0.840	0.730	<.001	74	view →
BRCA	OS	Tertile	III,IV	0.889	0.683	<.001	45	view →
LGG	OS	Median	All	0.945	0.827	<.001	34	view →
ACC	DFS	Quartile	All	0.297	0.772	.001	32	view →
COAD	DFS	Quartile	All	0.746	0.876	.001	28	view →
PCPG	DFS	Tertile	All	0.614	0.920	.006	25	view →
ESCA	DFS	Quartile	III,IV	0.210	0.482	.015	15	view →
CESC	OS	Median	II,III,IV	0.901	0.748	.008	14	view →
PAAD	DFS	Quartile	All	0.476	0.309	.026	10	view →
THCA	DFS	Median	All	0.969	0.899	.001	10	view →
BLCA	OS	Tertile	III,IV	0.226	0.564	.015	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

GLIDR–MESO (OS)

Open the MESO breakdown →