GLIDR

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, GLIDR Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated GLIDR data layer compared with 22 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher GLIDR Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated GLIDR expression acts as an unfavorable survival marker.

ESCA and KIRP are the cancer types where GLIDR Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCADFSMedianAll0.0810.536<.00121view →
KIRPDFSMedianAll0.1780.829<.00118view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

GLIDR–ESCA (DFS)

Kaplan–Meier survival curve for GLIDR mutant vs wild-type samples in ESCA.

Open the ESCA breakdown →

Exploration