GLE1

Across TCGA cell cohorts, GLE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,361 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GLE1-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, Poly(A)+ mRNA export from nucleus, and Immunoglobulin heavy chain V-D-J recombination. Each is linked with GLE1 in more than 15 cancer types. Because this analysis shows association rather than direction, both GLE1-to-partner and partner-to-GLE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome regulatory particle assembly grouped by GLE1-low versus GLE1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLE1→partner) and Y-score (partner→GLE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Proteasome regulatory particle assembly →	+0.118	+1.013	.002	.001	3	16
BONE	Poly(A)+ mRNA export from nucleus →	+0.137	+0.948	<.001	<.001	3	15
KIDNEY	Immunoglobulin heavy chain V-D-J recombination →	+0.225	+0.938	<.001	<.001	3	15
BONE	Regulation of chromatin organization →	+0.097	+0.628	<.001	<.001	3	14
STOMACH	Positive regulation of chromosome condensation →	+0.223	+0.683	<.001	.001	2	15
BLOOD_Myeloma	Interstrand cross-link repair →	+0.092	+0.852	<.001	.005	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,361 associations by consensus.

Proteasome regulatory particle assembly by GLE1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →