Across TCGA patient cohorts, GLDN protein abundance is significantly associated with the RNA expression of many other genes, with 2,108 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GLDN-associated genes across cancer lineages are APLP1, RASGEF1C, and ST18. Each is linked with GLDN in more than 1 cancer types. Because this analysis shows association rather than direction, both GLDN-to-partner and partner-to-GLDN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLDN→partner) and Y-score (partner→GLDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	APLP1 →	+1.093	+1.181	<.001	<.001	3	2
GBM	RASGEF1C →	+0.793	+0.615	.009	.004	3	2
GBM	ST18 →	+1.558	+0.769	<.001	<.001	3	2
GBM	PXK →	+0.702	+1.231	<.001	<.001	3	2
CCRCC	KCNQ3 →	+1.345	+0.585	.004	.001	3	2
CCRCC	LINC01877 →	+0.532	+0.653	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,108 associations by consensus.

Exploration

GLDN survival (RNA) · tumor vs normal (RNA) · all GLDN data types