Across TCGA cell cohorts, GLDN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,383 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GLDN-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Golgi vesicle transport. Each is linked with GLDN in more than 10 cancer types. Because this analysis shows association rather than direction, both GLDN-to-partner and partner-to-GLDN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLDN→partner) and Y-score (partner→GLDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of myoblast fusion →	+0.059	+0.917	.004	.005	3	11
BLOOD_Leukemia	Regulation of syncytium formation by plasma membrane fusion →	+0.053	+0.290	<.001	.002	3	9
LARGE_INTESTINE	Golgi vesicle transport →	+0.044	+0.657	<.001	.001	3	8
LUNG_NSCLC_LUSC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.061	+0.944	.006	.003	3	8
SOFT_TISSUE	SRP-dependent cotranslational protein targeting to membrane →	+0.078	+0.315	<.001	.002	3	7
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.069	+0.760	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,383 associations by consensus.

Exploration

GLDN survival (RNA) · tumor vs normal (RNA) · all GLDN data types