GLCE

Across TCGA cell cohorts, GLCE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,866 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GLCE-associated GO terms across cancer lineages are Circadian sleep/wake cycle, Regulation of attachment of spindle microtubules to kinetochore, and Regulation of chromosome organization. Each is linked with GLCE in more than 9 cancer types. Because this analysis shows association rather than direction, both GLCE-to-partner and partner-to-GLCE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Circadian sleep/wake cycle grouped by GLCE-low versus GLCE-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLCE→partner) and Y-score (partner→GLCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Circadian sleep/wake cycle →	+0.152	+1.361	.001	<.001	3	8
BLOOD_Lymphoma	Regulation of attachment of spindle microtubules to kinetochore →	+0.063	+0.766	.008	.007	1	10
KIDNEY	Regulation of chromosome organization →	+0.061	+0.815	.005	.009	3	8
OVARY	Regulation of nuclear cell cycle DNA replication →	+0.088	+0.788	.007	.003	3	8
CNS	Epigenetic regulation of gene expression →	+0.039	+0.778	<.001	<.001	3	8
BONE	Nuclear pore organization →	+0.154	+1.602	.005	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,866 associations by consensus.

Circadian sleep/wake cycle by GLCE expression — LUNG_SCLC

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