GLCCI1-DT

Across TCGA pan-cancer cohorts, GLCCI1-DT RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated GLCCI1-DT data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GLCCI1-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated GLCCI1-DT expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, HNSC, and BLCA are the cancer types where GLCCI1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.780	0.619	<.001	93	view →
HNSC	DFS	Quartile	IV	0.474	0.268	.010	30	view →
BLCA	OS	Tertile	All	0.679	0.309	.005	22	view →
READ	DFS	Quartile	II,III,IV	0.751	0.414	.011	21	view →
LUSC	DFS	Tertile	All	0.563	0.797	.006	19	view →
SKCM	OS	Median	IV	0.701	0.179	.005	15	view →
SARC	DFS	Tertile	All	0.605	0.456	.010	12	view →
ACC	DFS	Tertile	All	0.756	0.457	.036	10	view →
KIRC	DFS	Median	III,IV	0.579	0.318	.011	8	view →
LGG	DFS	Median	All	0.867	0.794	.005	8	view →
STAD	OS	Quartile	IV	0.328	0.693	.044	6	view →
UVM	OS	Tertile	III,IV	0.933	0.606	.043	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

GLCCI1-DT–LUAD (OS)

Open the LUAD breakdown →