GLB1L3

Across TCGA patient cohorts, GLB1L3 mutation is significantly associated with the RNA expression of many other genes, with 4,680 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLB1L3-associated genes across cancer lineages are CCL5, PSMA6, and LACTB. Each is linked with GLB1L3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLB1L3-to-partner and partner-to-GLB1L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL5 grouped by GLB1L3-low versus GLB1L3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLB1L3→partner) and Y-score (partner→GLB1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CCL5 →	+1.882	+3.459	<.001	.005	3	3
UCEC	PSMA6 →	+0.388	+2.008	.004	.001	3	3
UCEC	LACTB →	+0.504	+2.491	<.001	<.001	3	3
UCEC	ZBTB17 →	+0.314	+3.129	<.001	<.001	3	3
COAD	RPA2 →	+0.560	+3.513	<.001	.002	3	3
UCEC	ITGB1BP1 →	+0.254	+1.601	.005	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,680 associations by consensus.

CCL5 by GLB1L3 expression — COAD

Explore this box plot interactively →