GLB1L3

Across TCGA patient cohorts, GLB1L3 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLB1L3-associated genes across cancer lineages are ATM, Cyclin-B1, and eIF4E. Each is linked with GLB1L3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLB1L3-to-partner and partner-to-GLB1L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by GLB1L3-low versus GLB1L3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLB1L3→partner) and Y-score (partner→GLB1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.328	-1.571	.016	.032	3	3
UCEC	Cyclin-B1 →	+0.466	+1.999	.006	<.001	3	3
UCEC	eIF4E →	+0.177	+3.713	.005	<.001	3	2
UCEC	MEK1 →	+0.403	+2.459	<.001	<.001	3	2
UCEC	Annexin-1 →	+0.373	+1.125	.019	.033	3	2
UCEC	CD49b →	-0.294	-3.893	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

ATM by GLB1L3 expression — UCEC

Explore this box plot interactively →