GLB1L3

Across TCGA cell cohorts, GLB1L3 mutation is significantly associated with the mutation status of many other genes, with 5,698 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GLB1L3-associated genes across cancer lineages are CHD7, CACNA1I, and AP3B2. Each is linked with GLB1L3 in more than 4 cancer types. Because this analysis shows association rather than direction, both GLB1L3-to-partner and partner-to-GLB1L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHD7 grouped by GLB1L3-low versus GLB1L3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLB1L3→partner) and Y-score (partner→GLB1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CHD7 →	+1.632	+2.502	.005	.005	1	5
BLOOD_Leukemia	CACNA1I →	+3.115	+4.080	.001	.001	1	4
BREAST	AP3B2 →	+5.297	+5.297	.004	.004	1	4
LUNG_NSCLC_LUAD	CELF4 →	+5.303	+4.339	<.001	<.001	1	4
BLOOD_Leukemia	INO80D →	+3.285	+4.209	<.001	<.001	1	4
BLOOD_Leukemia	PARD3B →	+3.700	+4.498	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,698 associations by consensus.

CHD7 by GLB1L3 expression — LARGE_INTESTINE

Explore this box plot interactively →