GLB1L2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GLB1L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,891 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GLB1L2-associated GO terms across cancer lineages are Oncostatin-M-mediated signaling pathway, Extracellular structure organization, and Endoderm development. Each is linked with GLB1L2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GLB1L2-to-partner and partner-to-GLB1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oncostatin-M-mediated signaling pathway grouped by GLB1L2-low versus GLB1L2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLB1L2→partner) and Y-score (partner→GLB1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEOncostatin-M-mediated signaling pathway →-0.260-4.106<.001<.00139
BONEExtracellular structure organization →-0.200-3.073<.001<.00138
SOFT_TISSUEEndoderm development →-0.163-1.722<.001<.00138
STOMACHEstablishment of epithelial cell apical/basal polarity →-0.229-2.339<.001.00229
BONEExtracellular matrix organization →-0.200-3.073<.001<.00138
KIDNEYXenobiotic transmembrane transport →+0.177+1.879.001.00438
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,891 associations by consensus.

Oncostatin-M-mediated signaling pathway by GLB1L2 expression — BONE

Box plot of Oncostatin-M-mediated signaling pathway in GLB1L2-low vs GLB1L2-high samples in BONE.

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Exploration