GLB1L

Across TCGA patient cohorts, GLB1L protein abundance is significantly associated with the RNA expression of many other genes, with 3,247 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GLB1L-associated genes across cancer lineages are SMIM10L2B, KCNQ1, and LIG1. Each is linked with GLB1L in more than 2 cancer types. Because this analysis shows association rather than direction, both GLB1L-to-partner and partner-to-GLB1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLB1L versus SMIM10L2B in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLB1L→partner) and Y-score (partner→GLB1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SMIM10L2B →	+0.814	+0.518	.005	.001	3	2
UCEC	KCNQ1 →	+0.997	+0.347	.004	.007	3	2
GBM	LIG1 →	-0.899	-0.685	<.001	<.001	3	2
LUAD	TRIM14 →	-0.775	-0.391	.001	.008	3	2
GBM	MCM3 →	-0.562	-0.478	.006	.004	3	2
LUAD	ZNF346 →	-0.461	-0.450	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,247 associations by consensus.

GLB1L vs SMIM10L2B — BRCA

Explore this scatter interactively →