GLB1L

Across TCGA patient cohorts, GLB1L mutation is significantly associated with the RNA expression of many other genes, with 2,090 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLB1L-associated genes across cancer lineages are RNU7-121P, BRD9P1, and SNX3P1Y. Each is linked with GLB1L in more than 2 cancer types. Because this analysis shows association rather than direction, both GLB1L-to-partner and partner-to-GLB1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-121P grouped by GLB1L-low versus GLB1L-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLB1L→partner) and Y-score (partner→GLB1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU7-121P →	+0.420	+5.463	<.001	.005	3	3
LUSC	BRD9P1 →	+0.226	+4.906	<.001	.003	3	3
UCEC	SNX3P1Y →	+0.060	+3.723	<.001	.008	3	2
UCEC	BNIP3P41 →	+0.008	+3.723	<.001	.008	3	2
UCEC	RN7SKP132 →	+0.057	+2.761	.002	.009	3	2
UCEC	RNA5SP417 →	+0.446	+2.199	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,090 associations by consensus.

RNU7-121P by GLB1L expression — STAD

Explore this box plot interactively →