GLB1

Across TCGA patient cohorts, GLB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,612 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GLB1-associated proteins across cancer lineages are S100A11, MANF, and NNMT. Each is linked with GLB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GLB1-to-partner and partner-to-GLB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLB1 versus S100A11 in GBM, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GLB1→partner) and Y-score (partner→GLB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	S100A11 →	+0.749	+0.390	<.001	<.001	3	4
OV	MANF →	+0.410	+0.472	.001	.004	3	4
GBM	NNMT →	+1.060	+0.349	.002	.001	3	4
BRCA	GOLGA4 →	+0.241	+0.365	<.001	<.001	3	4
COAD	HSD17B4 →	+0.418	+0.412	.006	.002	2	5
GBM	PLOD3 →	+0.468	+0.260	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,612 associations by consensus.

GLB1 vs S100A11 — GBM

Explore this scatter interactively →