GLA

Across TCGA patient cohorts, GLA RNA expression is significantly associated with the protein abundance of many other proteins, with 12,196 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GLA-associated proteins across cancer lineages are PHPT1, NCF2, and G6PD. Each is linked with GLA in more than 4 cancer types. Because this analysis shows association rather than direction, both GLA-to-partner and partner-to-GLA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLA versus PHPT1 in LSCC, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GLA→partner) and Y-score (partner→GLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PHPT1 →	-0.352	-0.643	<.001	<.001	3	5
GBM	NCF2 →	+0.554	+0.345	.001	<.001	3	5
LSCC	G6PD →	+0.840	+0.715	<.001	<.001	3	5
CCRCC	HK3 →	+0.644	+0.545	<.001	<.001	3	5
BRCA	PYCARD →	+0.524	+0.604	.006	<.001	3	5
LSCC	CUL1 →	+0.170	+0.404	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,196 associations by consensus.

GLA vs PHPT1 — LSCC

Explore this scatter interactively →