GLA

Across TCGA patient cohorts, GLA protein abundance is significantly associated with the RNA expression of many other genes, with 15,743 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GLA-associated genes across cancer lineages are FTL, SRPX2, and SLC10A3. Each is linked with GLA in more than 3 cancer types. Because this analysis shows association rather than direction, both GLA-to-partner and partner-to-GLA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLA versus FTL in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLA→partner) and Y-score (partner→GLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FTL →	+0.794	+0.304	<.001	<.001	3	4
COAD	SRPX2 →	+1.025	+0.457	<.001	.001	3	3
GBM	SLC10A3 →	+0.536	+0.379	<.001	<.001	3	3
GBM	BTBD11 →	+0.962	+0.332	.004	.001	3	3
LSCC	ZBTB33 →	+0.460	+0.246	.002	.007	3	3
LSCC	BCAP31 →	+0.523	+0.501	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,743 associations by consensus.

GLA vs FTL — GBM

Explore this scatter interactively →