Across TCGA patient cohorts, GKN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,077 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GKN2-associated proteins across cancer lineages are IGBP1, IGKV1D-13, and NOP10. Each is linked with GKN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GKN2-to-partner and partner-to-GKN2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GKN2→partner) and Y-score (partner→GKN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	IGBP1 →	-0.186	-0.071	<.001	.005	3	3
COAD	IGKV1D-13 →	+0.766	+0.056	.005	.008	3	3
LSCC	NOP10 →	-0.221	-0.703	<.001	<.001	3	3
LSCC	MLPH →	+0.689	+1.228	<.001	<.001	3	3
LUAD	OGN →	+0.637	+1.515	<.001	<.001	3	3
LUAD	OLFML1 →	+0.606	+1.919	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,077 associations by consensus.

Exploration

GKN2 survival (RNA) · tumor vs normal (RNA) · all GKN2 data types