Across TCGA patient cohorts, GKN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,829 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible GKN2-associated GO terms across cancer lineages are Regulation of actomyosin structure organization, Prostanoid biosynthetic process, and Vesicle targeting, to, from or within Golgi. Each is linked with GKN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GKN2-to-partner and partner-to-GKN2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GKN2→partner) and Y-score (partner→GKN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Regulation of actomyosin structure organization →	+0.016	+0.074	<.001	.001	3	7
LUAD	Prostanoid biosynthetic process →	+0.023	+0.782	<.001	<.001	3	7
DLBC	Vesicle targeting, to, from or within Golgi →	+0.059	+0.111	.003	.003	2	8
LUSC	Regulation of small GTPase mediated signal transduction →	+0.023	+1.117	<.001	<.001	3	7
LUSC	Actin filament bundle organization →	+0.031	+0.847	<.001	<.001	3	7
READ	Cytosolic transport →	+0.020	+0.025	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,829 associations by consensus.

Exploration

GKN2 survival (RNA) · tumor vs normal (RNA) · all GKN2 data types