GKN2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GKN2 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,735 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GKN2-associated proteins across cancer lineages are BCAS2, ACTR1A, and BMPER. Each is linked with GKN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GKN2-to-partner and partner-to-GKN2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GKN2→partner) and Y-score (partner→GKN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCBCAS2 →-0.183-0.541.001.00132
LSCCACTR1A →+0.162+0.557.001.00132
LSCCBMPER →+0.451+0.701<.001<.00132
LUADBRCA1_S114 →-0.779-1.224.001<.00132
LSCCBRCA1_S1524 →-0.734-0.658<.001<.00132
LUADBRIP1_T989 →-0.761-1.119<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,735 associations by consensus.

Exploration