Across TCGA cell cohorts, GKN2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GKN2-associated genes across cancer lineages are FAM153B and TAFA1. Each is linked with GKN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GKN2-to-partner and partner-to-GKN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GKN2→partner) and Y-score (partner→GKN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM153B →	+0.537	+3.618	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

GKN2 survival (RNA) · tumor vs normal (RNA) · all GKN2 data types