GKN1

Across TCGA patient cohorts, GKN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,796 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GKN1-associated GO terms across cancer lineages are Prostanoid metabolic process, Negative regulation of protein-containing complex assembly, and Mitochondrial electron transport, ubiquinol to cytochrome c. Each is linked with GKN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GKN1-to-partner and partner-to-GKN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Prostanoid metabolic process grouped by GKN1-low versus GKN1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GKN1→partner) and Y-score (partner→GKN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Prostanoid metabolic process →	+0.061	+2.241	<.001	<.001	3	7
UCEC	Negative regulation of protein-containing complex assembly →	+0.023	+0.059	<.001	.001	3	6
UCEC	Mitochondrial electron transport, ubiquinol to cytochrome c →	+0.036	+0.069	<.001	.003	3	5
LIHC	Negative regulation of programmed necrotic cell death →	+0.052	+0.021	<.001	.002	3	5
STAD	Cellular response to xenobiotic stimulus →	+0.030	+2.001	<.001	<.001	3	5
ESCA	Positive regulation of nitric oxide metabolic process →	+0.046	+0.991	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,796 associations by consensus.

Prostanoid metabolic process by GKN1 expression — STAD

Explore this box plot interactively →