GKN1

Across TCGA patient cohorts, GKN1 protein abundance is significantly associated with the RNA expression of many other genes, with 674 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GKN1-associated genes across cancer lineages are C3orf14, S100PBP, and PRDM7. Each is linked with GKN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GKN1-to-partner and partner-to-GKN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GKN1 versus C3orf14 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GKN1→partner) and Y-score (partner→GKN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C3orf14 →	-0.793	-0.455	.001	<.001	3	1
LSCC	S100PBP →	-0.278	-0.414	.004	.001	3	1
LSCC	PRDM7 →	-0.114	-0.516	.004	<.001	3	1
LSCC	CCL21 →	+1.817	+0.488	<.001	.002	3	1
LSCC	NTRK3 →	+0.250	+0.448	<.001	.003	3	1
LSCC	FABP2 →	-0.314	-0.389	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 674 associations by consensus.

GKN1 vs C3orf14 — LSCC

Explore this scatter interactively →