GKAP1

Across TCGA patient cohorts, GKAP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,683 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GKAP1-associated proteins across cancer lineages are SMC1A, CBX1, and HCFC1. Each is linked with GKAP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GKAP1-to-partner and partner-to-GKAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GKAP1 versus SMC1A in LSCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GKAP1→partner) and Y-score (partner→GKAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMC1A →	+0.329	+0.783	<.001	<.001	3	8
GBM	CBX1 →	+0.418	+0.475	.001	.003	3	8
GBM	HCFC1 →	+0.240	+0.479	.001	.001	3	7
CCRCC	PLAU →	-0.883	-0.515	.002	.001	3	7
LSCC	MYEF2 →	+0.818	+0.631	<.001	<.001	3	7
BRCA	ACTR2 →	-0.194	-0.452	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,683 associations by consensus.

GKAP1 vs SMC1A — LSCC

Explore this scatter interactively →