GKAP1

Across TCGA patient cohorts, GKAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,362 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GKAP1-associated genes across cancer lineages are POLI, DYM, and S100A8. Each is linked with GKAP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GKAP1-to-partner and partner-to-GKAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GKAP1 versus POLI in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GKAP1→partner) and Y-score (partner→GKAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	POLI →	+0.552	+0.625	.001	.002	3	5
LSCC	DYM →	+0.610	+0.728	<.001	<.001	3	5
HNSC	S100A8 →	-2.857	-0.808	.005	.003	3	5
HNSC	KLF15 →	+1.711	+1.248	<.001	<.001	3	5
HNSC	CCDC171 →	+0.844	+0.815	.001	.002	3	5
HNSC	SALL2 →	+1.245	+0.801	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,362 associations by consensus.

GKAP1 vs POLI — LSCC

Explore this scatter interactively →