GKAP1

Across TCGA cell cohorts, GKAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,456 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GKAP1-associated GO terms across cancer lineages are Regulation of centrosome cycle, Chemotaxis, and External encapsulating structure organization. Each is linked with GKAP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both GKAP1-to-partner and partner-to-GKAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centrosome cycle grouped by GKAP1-low versus GKAP1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GKAP1→partner) and Y-score (partner→GKAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of centrosome cycle →	+0.120	+1.007	<.001	<.001	3	12
BONE	Chemotaxis →	-0.095	-1.406	.001	<.001	3	12
BONE	External encapsulating structure organization →	-0.226	-1.404	<.001	<.001	3	12
BONE	Extracellular matrix disassembly →	-0.158	-1.214	<.001	.001	3	12
BONE	Cell-substrate adhesion →	-0.168	-1.619	.001	<.001	3	12
BONE	Taxis →	-0.095	-1.406	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,456 associations by consensus.

Regulation of centrosome cycle by GKAP1 expression — LUNG_SCLC

Explore this box plot interactively →