Across TCGA patient cohorts, GK2 RNA expression is significantly associated with the RNA expression of many other genes, with 5,505 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GK2-associated genes across cancer lineages are HMGB4, ATG10-AS1, and LINC00317. Each is linked with GK2 in more than 11 cancer types. Because this analysis shows association rather than direction, both GK2-to-partner and partner-to-GK2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GK2→partner) and Y-score (partner→GK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	HMGB4 →	+0.680	+0.540	<.001	<.001	3	12
COAD	ATG10-AS1 →	+0.698	+0.016	<.001	<.001	3	11
SARC	LINC00317 →	+0.563	+0.022	<.001	.002	3	11
LIHC	ZNF385D-AS2 →	+0.533	+0.077	<.001	<.001	3	11
DLBC	RNU2-3P →	+0.595	+0.169	<.001	<.001	3	11
PCPG	LINC00290 →	+1.114	+0.004	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,505 associations by consensus.

Exploration

GK2 survival (RNA) · tumor vs normal (RNA) · all GK2 data types