GJD4

Across TCGA patient cohorts, GJD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,112 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GJD4-associated GO terms across cancer lineages are Positive regulation of canonical Wnt signaling pathway, Mesenchymal cell differentiation, and Maintenance of cell number. Each is linked with GJD4 in more than 23 cancer types. Because this analysis shows association rather than direction, both GJD4-to-partner and partner-to-GJD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of canonical Wnt signaling pathway grouped by GJD4-low versus GJD4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GJD4→partner) and Y-score (partner→GJD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of canonical Wnt signaling pathway →	+0.055	+0.135	<.001	<.001	3	24
STAD	Mesenchymal cell differentiation →	+0.048	+0.130	<.001	<.001	3	24
STAD	Maintenance of cell number →	+0.052	+0.141	<.001	<.001	3	23
UCS	Negative regulation of growth →	+0.044	+1.960	<.001	<.001	3	23
STAD	Rac protein signal transduction →	+0.055	+0.148	<.001	<.001	3	23
SCLC	Developmental growth involved in morphogenesis →	+0.047	+0.345	.009	.002	2	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,112 associations by consensus.

Positive regulation of canonical Wnt signaling pathway by GJD4 expression — STAD

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