GJD4

Across TCGA cell cohorts, GJD4 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GJD4-associated genes across cancer lineages are OBP2B, CNGA2, and GALP. Each is linked with GJD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJD4-to-partner and partner-to-GJD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OBP2B grouped by GJD4-low versus GJD4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJD4→partner) and Y-score (partner→GJD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OBP2B →	+0.057	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	CNGA2 →	+0.074	+4.539	<.001	.007	3	1
BLOOD_Leukemia	GALP →	+0.059	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	CCT8L2 →	+0.011	+4.874	<.001	.002	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.092	+4.539	<.001	.007	3	1
LARGE_INTESTINE	MAGEB1 →	+0.159	+2.878	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OBP2B by GJD4 expression — BLOOD_Leukemia

Explore this box plot interactively →