GJD3

Across TCGA patient cohorts, GJD3 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GJD3-associated genes across cancer lineages are RNA5SP415, LINC02590, and RNU7-165P. Each is linked with GJD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJD3-to-partner and partner-to-GJD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP415 grouped by GJD3-low versus GJD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJD3→partner) and Y-score (partner→GJD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP415 →	+1.192	+4.073	<.001	.004	3	2
UCEC	LINC02590 →	+0.172	+3.936	<.001	.005	3	1
UCEC	RNU7-165P →	+0.505	+4.750	<.001	.005	3	1
UCEC	RNA5SP419 →	+1.414	+3.661	<.001	.009	3	1
UCEC	RNA5SP410 →	+1.514	+4.789	<.001	.001	3	1
UCEC	RNA5SP413 →	+2.374	+4.277	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

RNA5SP415 by GJD3 expression — UCEC

Explore this box plot interactively →